Endocrine Abstracts

Introduction: Obesity lowers adiponectin levels. Adiponectin has anti-inflammatory effects. It has been suggested that the lower levels of adiponectin in obesity results in chronic low grade inflammation (CLGI). Aim of this study was to examine if plasma adiponectin is a valid marker of CLGI in normal weight, overweight and obese individuals. In addition, we also assessed adiponectin as marker of body fat and insulin resistanceMethods: We measured adipon...

We have previously shown that Corticotropin – releasing factor (CRF) and Urocortins (UCNs) induce the production of catecholamines from normal human and rat adrenal chromaffin and PC12 pheochomocytoma cells via induction of tyrosine hydroxylase, the rate limiting enzyme of catecholamine biosynthesis. We have also shown that CRF induces calcium ion entrance into the cytoplasm from both extracellular sources (influx) and from intracellular stores (mobilization) in PC12 cell...